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Submitted: 06 Aug 2020
Accepted: 27 Sep 2020
ePublished: 15 Oct 2020
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  Abstract View: 848

Original

Musculoskeletal manifestation of kidney transplant recipients

Karim Mowla 1 ORCID logo, Hajieh Shahbazian 2, Asghar Sharif Najafi 3 ORCID logo, Ali Ghorbani 4* ORCID logo

1 Unit of Rheumatology, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
2 Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
3 School of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
4 4Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
*Corresponding author: Ali Ghorbani, Email: ali.ghorbani.001@gmail.com, ghorbani-a@ajums.ac.ir

Abstract

Introduction: Kidney transplantation has been established as an effective treatment method for patients with end-stage renal disease.

Objectives: The purpose of this study was to determine the prevalence of musculoskeletal complaints following kidney transplant.

Patient and Methods: We designed a retrospective-descriptive study on kidney transplant recipients. This study was performed on medical records of 1189 kidney transplant patients referring to the kidney transplantation ward of Golestan hospital (Ahvaz, Iran).

Results: The mean age of the participants was 42.8 ± 13.5 years. Out of the 1189 patients, 231 (22.3%) had musculoskeletal manifestations, with the most prevalent problem being non-inflammatory pain (41.4%). Additionally, degenerative joint disease, especially in the lumbar spine, was the most common clinical finding in this study (24%). Besides, hypovitaminose D (71.4%) and elevated parathyroid hormone levels (51.3%) and hyperuricemia (50.8%) were the most common laboratory abnormalities observed in our patients.

Conclusion: Approximately 22.3% of our renal transplant patients had musculoskeletal manifestations. Attention to earlier detection of these manifestations through regular examinations would reduce the complications and burden of the disease.

Keywords: Kidney transplantation, Musculoskeletal manifestation, Transplantation, End-stage renal disease, Bone-mineral densitometry
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