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Submitted: 03 Sep 2024
Revision: 30 Oct 2024
Accepted: 27 Dec 2024
ePublished: 27 Apr 2025
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J Renal Inj Prev. 2025;14(3): e38409.
doi: 10.34172/jrip.2025.38409
  Abstract View: 2
  PDF Download: 3

Mini-Review

SGLT2 inhibitors for the treatment of pulmonary hypertension; new trends

Mohammad Memarian ORCID logo, Rahimeh Eskandarian* ORCID logo

1 Clinical Research Development Unit, Kowsar Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran
*Corresponding Author: Rahimeh Eskandarian, Email: rheskandarian@yahoo.com

Abstract

The landscape of pulmonary hypertension (PAH) treatment is evolving, with SGLT2 inhibitors being recognized as a potential fourth treatment pathway alongside traditional therapies. Their incorporation into treatment strategies for PAH could represent a significant shift in management approaches.

Implication for health policy/practice/research/medical education:

Sodium-glucose co-transporter 2 (SGLT2) inhibitors show promise in treating pulmonary hypertension (PAH) through their multifaceted effects on metabolism, vascular function, and hemodynamics.

Please cite this paper as: Memarian M, Eskandarian R. SGLT2 inhibitors for the treatment of pulmonary hypertension; new trends. J Renal Inj Prev. 2025; 14(3): e38409. doi: 10.34172/jrip.2025.38409.

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