Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 11 2 2022 06 01 On admission hemoglobin and albumin, as the two novel factors associated with thrombosis in COVID-19 pneumonia e31957 e31957 10.34172/jrip.2022.31957 EN Somayeh Sadeghi https://orcid.org/0000-0003-4287-1720 Peiman Nasri https://orcid.org/0000-0001-5887-7583 Maryam Nasirian https://orcid.org/0000-0002-8365-3845 Maryam Sadat Mirenayat https://orcid.org/0000-0002-0852-1666 Arash Toghyani https://orcid.org/0000-0003-2342-7982 Mohammadsaeid Khaksar https://orcid.org/0000-0003-1194-6742 Elahe Nasri https://orcid.org/0000-0001-9963-7084 Ali Safaei https://orcid.org/0000-0001-8718-6650 Hamed Fakhim https://orcid.org/0000-0002-0517-7994 Elham Raofi https://orcid.org/0000-0001-9767-6346 Koorosh Nemati https://orcid.org/0000-0003-0921-9722 Hurie Hashemi https://orcid.org/0000-0003-3412-1997 Elaheh Keivany https://orcid.org/0000-0002-0932-5093 Journal Article 10.34172/jrip.2022.31957 2021 09 16 2021 11 01 Introduction: The unrelenting storm of coronavirus disease (COVID-19) since late 2019 has turned into a crucial health matter of the globe. There is increasing evidence in terms of a hypercoagulable state by this infection. Objectives: The current study aims to clarify the association between thromboembolic events in COVID-19 and the patient, the infection and in-hospital related characteristics. Patients and Methods: The current case-control study has been conducted on 243 COVID-19 pneumonia patients including 83 cases with thrombotic events and 160 controls without thrombosis. The thrombotic events included deep venous thrombosis (DVT) (n=9), pulmonary thromboembolism (PTE) (n=48), acute myocardial infarction (AMI) (n=17), cerebrovascular accidents (CVA) (n=4) and arterial thrombosis (n=5). On admission, hemodynamic parameters, on admission laboratory assessments, mobility during hospitalization, type of oxygenation, intensive care unit (ICU) admission requirement and duration of ICU and also hospital stay were recorded in the checklist. Results: According to logistic regression assessment, on admission O2 saturation (OR: 0.97, 95% CI: 0.94-0.99), hemoglobin level (OR: 0.87, 95% CI: 0.77-0.97) and albumin level (OR: 0.53, 95% CI: 0.3-0.86) were independently correlated with thrombosis due to COVID-19. Other factors, including demographic, infection severity, laboratory and in-hospital characteristics, were not significantly associated with thrombotic events. Conclusion: Based on this study’s findings, hemoglobin and albumin levels were the independent factors associated with the thrombotic events in COVID-19 patients.