Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 12 4 2023 12 01 Possible amelioration impact of sodium-glucose cotransporter 2 inhibitors on cisplatin-induced renal toxicity; a mini-review on recent findings e32245 e32245 10.34172/jrip.2023.32245 EN Parisa Keshtgar https://orcid.org/0009-0007-6243-8306 Leila Mahmoodnia https://orcid.org/0000-0002-0495-4683 Samin Karamian https://orcid.org/0009-0004-7650-2610 Journal Article 10.34172/jrip.2023.32245 2023 07 17 2023 09 26 Cisplatin-induced nephrotoxicity is a crucial concern in cancer patients, limiting the dose and duration of cisplatin therapy. Several mechanisms contribute to cisplatin nephrotoxicity, including oxidative stress, inflammation, and mitochondrial dysfunction. SGLT2 inhibitors have emerged as a promising therapeutic option for various renal disorders due to their ability to restore renal homeostasis and mitigate renal injury