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J Renal Inj Prev. 2016;5(4): 179-182. doi: 10.15171/jrip.2016.38
PMID: 27689119        PMCID: PMC5039985

Original Article

Effect of selenium supplementation on lipid profile in hemodialysis patients

Hamidreza Omrani 1, Sima Golmohamadi 1 * , Yahya Pasdar 2, Kambiz Jasemi 3, Afshin Almasi 4

Cited by CrossRef: 23


1- Badri S, Vahdat S, Pourfarzam M, Assarzadeh S, Seirafian S, Ataei S. Potential Benefits of Selenium Supplementation in Patients with Kidney Disease. 2021;10(4):149 [Crossref]
2- Neamah N, Naaeem Khudair A, Al-Jadaan S. Comparative evaluation of biochemical profiling of 4’, 4”- (4, 5, 6, 7-TETRAHYDRO- [1, 2, 3-] SELENADIAZOLO [4, 5e] PYRIDINE-4, 6-DIYL) BIS (BENZENE-1, 3-DIOL) and dipyrone on female rat’s. J Phys: Conf Ser. 2019;1279(1):012033 [Crossref]
3- Salimian M, Soleimani A, Bahmani F, Tabatabaei S, Asemi Z, Talari H. The effects of selenium administration on carotid intima-media thickness and metabolic status in diabetic hemodialysis patients: A randomized, double-blind, placebo-controlled trial. Clinical Nutrition ESPEN. 2022;47:58 [Crossref]
4- Zhu M, Gao Z, Lu J, Wang Y, Wang G, Zhu T, Li P, Liu C, Wang S, Yang L. Amorphous nano-selenium quantum dots prevent pulmonary arterial hypertension through recoupling endothelial nitric oxide synthase. Aging. 2021;13(3):3368 [Crossref]
5- Parisi O, Ruffo M, Amone F, Malivindi R, Gorgoglione D, De Biasio F, Scrivano L, Pezzi V, Puoci F. PDO Rotonda’s Red Eggplant Extract: In vitro Determination of Biological Properties and Minerals Bioaccessibility. CNF. 2020;16(1):65 [Crossref]
6- Padoan F, Guarnaroli M, Brugnara M, Piacentini G, Pietrobelli A, Pecoraro L. Role of Nutrients in Pediatric Non-Dialysis Chronic Kidney Disease: From Pathogenesis to Correct Supplementation. Biomedicines. 2024;12(4):911 [Crossref]
7- Rodrigues R, Nascimento D, Brito J, Lima L, Lobo J, Cardozo L, Mafra D. Brazil nut or not? Uncovering the best source of selenium for chronic non-communicable disease. Food Bioscience. 2025;68:106520 [Crossref]
8- Zhu M, Wang G, Wang H, Guo Y, Song P, Xu J, Li P, Wang S, Yang L. Amorphous nano-selenium quantum dots improve endothelial dysfunction in rats and prevent atherosclerosis in mice through Na+/H+ exchanger 1 inhibition. Vascular Pharmacology. 2019;115:26 [Crossref]
9- Cheng Q, Fan D, Chen P, Yuan H. Effect of selenium supplementation on hemodialysis patients: a meta-analysis. Int Urol Nephrol. 2025; [Crossref]
10- Kelishadi M, Ashtary-Larky D, Davoodi S, Clark C, Asbaghi O. The effects of selenium supplementation on blood lipids and blood pressure in adults: A systematic review and dose-response meta-analysis of randomized control trials. Journal of Trace Elements in Medicine and Biology. 2022;74:127046 [Crossref]
11- Yousefi Rad E, Falahi E, Saboori S, Asbaghi O, Birjandi M, Hesami S, Aghayan M. Effect of selenium supplementation on lipid profile levels: An updated systematic review and meta-analysis of randomized controlled clinical trials. Obesity Medicine. 2019;15:100113 [Crossref]
12- Sabet H, Jalali M, Rezaei H, Rezaei T, Motamed M, Keshavarzian O, Nematolahi S. The Effects of Selenium Supplementation on Lipid Profile and the Inflammatory and Oxidative Stress Markers in Patients With Kidney Diseases. 2025; [Crossref]
13- Fu S, Zhang L, Ma F, Xue S, Sun T, Xu Z. Effects of Selenium on Chronic Kidney Disease: A Mendelian Randomization Study. Nutrients. 2022;14(21):4458 [Crossref]
14- Atapour A, Vahdat S, Hosseini M, Mohamadian H. Effect of Selenium on Triglyceride and Total Cholesterol, Weight Gain, and Physical Activity on Hemodialysis Patients. 2022;13(1):63 [Crossref]
15- Saadh M, Khaleel A, Merza M, Hassan H, Tomar B, Singh M, Kumar A, Hasaanzadeh S. The effects of selenium supplementation on lipid profile in adults: A systematic review and meta-analysis of randomized controlled trials. Prostaglandins & Other Lipid Mediators. 2024;175:106901 [Crossref]
16- Kamali A, Amirani E, Asemi Z. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial. Biol Trace Elem Res. 2019;191(2):331 [Crossref]
17- Li Z, Lai J, Wen L, Chen Q, Tan R, Zhong X, Liu Y, Liu Y. Higher Levels of Blood Selenium are Associated with Higher Levels of Serum Lipid Profile in US Adults with CKD: Results from NHANES 2013–2018. Biol Trace Elem Res. 2023;201(12):5501 [Crossref]
18- Assarzadeh S, Vahdat S, Seirafian S, Pourfarzam M, Badri S. Effect of Selenium Supplementation on Lipid Profile, Anemia, and Inflammation Indices in Hemodialysis Patients. 2022;11(3):103 [Crossref]
19- Urbano T, Wise L, Fiore G, Vinceti M, Filippini T. Effects of Selenium Administration on Blood Lipids: A Systematic Review and Dose–Response Meta-Analysis of Experimental Human Studies. 2025; [Crossref]
20- Shi Y, Hu H, Wu Z, Chen Z, Li P. Blood selenium level can alleviate the nephrotoxicity of lead and cadmium in the general population of the United States: a retrospective cross section analysis of population‐based nationally representative data. Environ Sci Pollut Res. 2023;30(29):73497 [Crossref]
21- Drikvandi M, Jorfi S, Cheraghian B, Ahmadi M. Relationship between heavy metal concentrations and Chronic kidney disease in population of Hoveyzeh cohort study: A cross-sectional study in Iran. Journal of Trace Elements in Medicine and Biology. 2024;83:127412 [Crossref]
22- Trigueira P, Leal V, Cardoso B, Mafra D, Araujo M, Stockler-Pinto M. Selenium supplementation in chronic kidney disease patients undergoing haemodialysis: a systematic review of the effects on plasma selenium, antioxidant and inflammatory markers, immunological parameters and thyroid hormones. Nutr Res Rev. 2024;:1 [Crossref]
23- Panchal S, Wanyonyi S, Brown L. Selenium, Vanadium, and Chromium as Micronutrients to Improve Metabolic Syndrome. Curr Hypertens Rep. 2017;19(3) [Crossref]
24- Fu S, Qian M, Yuan Z, Su S, Ma F, Li F, Xu Z. A new perspective on selenium’s impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study. Front Endocrinol. 2024;15 [Crossref]
25- Yang T, Lee S, Park K, Park S, Chung J, Lee S. The Effects of Selenium on Bone Health: From Element to Therapeutics. Molecules. 2022;27(2):392 [Crossref]
26- Tonelli M, Wiebe N, Bello A, Field C, Gill J, Hemmelgarn B, Holmes D, Jindal K, Klarenbach S, Manns B, Thadhani R, Kinniburgh D. Concentrations of Trace Elements and Clinical Outcomes in Hemodialysis Patients. CJASN. 2018;13(6):907 [Crossref]