Severe symptomatic acute hyponatremia in traumatic brain injury responded very rapidly to a single 15 mg dose of oral tolvaptan; a Mayo Clinic Health System hospital experience – need for caution with tolvaptan in younger patients with preserved renal function

Macaulay Amechi Chukwukadibia Onuigbo ¹ * , Nneoma Agbasi ²

Cited by CrossRef: 2

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3- Petria I, Indirli R, Mantovani B, Lanzi V, Mantovani G, Ferrante E. Recurrent hyponatremia due to syndrome of inappropriate antidiuresis after traumatic brain injury: two case reports. Front Endocrinol. 2025;16 [Crossref]

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5- Tomkins M, Green D, O’Reilly M, Sherlock M. Fluid and electrolyte disorders following traumatic brain injury. Best Practice & Research Clinical Endocrinology & Metabolism. 2025;39(3):102014 [Crossref]