Glutathione ameliorates liver markers, oxidative stress and inflammatory indices in rats with renal ischemia reperfusion injury

Hassan Ahmadvand ^1,2, Esmaeel Babaeenezhad ^3,4 * , Maryam Nasri ³, Leila Jafaripour ⁵, Reza Mohammadrezaei Khorramabadi ³

Cited by CrossRef: 14

1- Chen H, Li X. WITHDRAWN: LncRNA-ROR is involved in cerebral hypoxia/reoxygenation-induced injury via regulating miR-135a-5p/ROCK1/2. Experimental and Molecular Pathology. 2019;:104298 [Crossref]

2- Eslamifar Z, Moridnia A, Sabbagh S, Ghaffaripour R, Jafaripour L, Behzadifard M, El-Demerdash F. Ameliorative Effects of Gallic Acid on Cisplatin‐Induced Nephrotoxicity in Rat Variations of Biochemistry, Histopathology, and Gene Expression. BioMed Research International. 2021;2021(1) [Crossref]

3- Babaeenezhad E, Dezfoulian O, Hadipour Moradi F, Rahimi Monfared S, Fattahi M, Nasri M, Amini A, Ahmadvand H. Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA. Drug and Chemical Toxicology. 2023;46(3):441 [Crossref]

4- Ahmadvand H, Nouryazdan N, Nasri M, Adibhesami G, Babaeenezhad E. Renoprotective Effects of Gallic Acid Against Gentamicin Nephrotoxicity Through Amelioration of Oxidative Stress in Rats. Braz arch biol technol. 2020;63 [Crossref]

5- Roshankhah S, Abdolmaleki A, Salahshoor M. Reduction of Renal Ischemia-Reperfusion-Induced Liver Side Effects in Rats through Antioxidative Properties of Narigenin. J Adv Med Biomed Res. 2021;29(132):46 [Crossref]

6- Lotfi B, Bagheri Y, Abdollahpour A, Ahmadian E, Matin S, Firouzfar A, Zununi Vahed S, Khajepour F. Protective effect of Eprosartan against ischemic acute renal injury: Acting on NF-κB, caspase 3, and Sirtuin 1. International Immunopharmacology. 2023;115:109690 [Crossref]

7- Mao M, Yu X, Tian G, Zhang L, Huang H, Chu Q. Discovery and functional validation of a novel lotus root-derived peptide (EWGHLGL) alleviating oxidative stress in vitro and in vivo. Food Chemistry. 2025;493:146013 [Crossref]

8- Li J, Cao J, Wu W, Xu L, Zhang S, Ma P, Wu Q, Song D. A molecular imaging tool for monitoring carboxylesterase 2 during early diagnosis of liver-related diseases. Sensors and Actuators B: Chemical. 2023;377:133122 [Crossref]

9- Babaeenezhad E, Nouryazdan N, Nasri M, Ahmadvand H, Moradi Sarabi M. Cinnamic acid ameliorate gentamicin-induced liver dysfunctions and nephrotoxicity in rats through induction of antioxidant activities. Heliyon. 2021;7(7):e07465 [Crossref]

10- Karimi-Dehkordi M, Saghaei F, Hoseini E. Inhibition of Inflammatory Signals “HMGB1, NLRP3, TNF-α, IL-1β” and Oxidative Stress in Diclofenac-Induced Hepatotoxicity in Rats Using Hydroalcoholic Extract of Dracocephalum kotschyi. Iran J Pharm Res. 2025;24(1) [Crossref]

11- Rostami R, Eslamifar Z, Nazemi S, Hosseini S, Behvandi M, Jafaripour L, Maciejczyk M. The Effect of Thyme Essential Oil on Liver Injuries Caused by Renal Ischemia‐Reperfusion in Rats. BioMed Research International. 2022;2022(1) [Crossref]

12- Khalifa M, Hassan F, Abdallah H, Bastawy N. Protective effect of grape seed extract against chronic physical stress‐induced zona fasciculata injury in male rats: Functional, immunohistochemical and electron microscopic study. Microscopy Res & Technique. 2022;85(8):2813 [Crossref]

13- Rahmani Moghadam E, Hosseini S, Naserzadeh R, Alizamani E, Ahmadvand H, Eslamifar Z, Jafaripour L. Alleviation of Renal Ischemia-Reperfusion–Induced Injuries by Anti-Inflammatory Attributes of Thyme Essential Oil in Male Rats: A Biochemical and Stereological Study. J Rep Pharm Sci. 2025;13(1) [Crossref]

14- Alizadeh M, Nafari A, Hadipour Moradi F, Beyranvand F, Ahmadvand H, Birjandi M, Bagheri S, Kiani A. The Effect of Wet Cupping (Al-hijamah) and Limonene on Oxidative Stress and Biochemical Parameters in Diabetic Rats. Jundishapur J Nat Pharm Prod. 2022;17(4) [Crossref]

15- Rahimi Monfared S, Valibeik A, Tavakoli Dastjerd N, Jafaripour L, Jafarian A, Nabi Moradi M, Ahmadvand H. Protective role of citronellol on antioxidant enzymes and oxidative damage induced by gentamicin in experimental nephrotoxic rats. Mol Biol Rep. 2024;51(1) [Crossref]

16- Kubota R, Hayashi N, Kinoshita K, Saito T, Ozaki K, Ueda Y, Tsuchishima M, Tsutsumi M, George J. Inhibition of γ‐glutamyltransferase ameliorates ischaemia‐reoxygenation tissue damage in rats with hepatic steatosis. British J Pharmacology. 2020;177(22):5195 [Crossref]

17- Silja K, Selvaganabathy N, Kalaiselvi T, Thirunavukkarasu C. Inhibition of glutathione generation in hepatic steatotic rats augments oxidative stress. Toxicology Mechanisms and Methods. 2023;33(7):596 [Crossref]