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ePublished: 10 Oct 2013
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J Renal Inj Prev. 2013;2(4): 127-128.
doi: 10.12861/jrip.2013.41
PMID: 25340150
PMCID: PMC4206026
  Abstract View: 1549
  PDF Download: 759

Letter to Editor

Light chain deposition disease; there are reasons for confusion

Mohammad-Reza Ardalan 1 *

1 Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding author: Prof. Mohammad-Reza Ardalan, Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ardalan34@yahoo.comcom

Abstract

Implication for health policy/practice/research/medical education:Congo red negative nodular deposition of an amorphous, eosinophilic material is the most common pathologic finding in light chain deposition disease in light microscopy. The nodules are a mixture of light chain and mesangial protein and the picture is reminiscent of diabetic nephropathy. Immunoflurescent microscopy usually demonstrates the presence of monotypic kappa light chain. It seems that serum creatinine level greater than 4 mg/dl is a poor prognosis sign for future progress to end stage renal disease in this disease. Therefore, early diagnosis is important.
Keywords: Light chain deposition disease, Plasma cell dyscrasia, Glycosuria
Please cite this paper as: Ardalan MR. Mycobacterial disease in renal allograft recipients. J Ren Inj Prev 2013; 2(4): 127-128. DOI: 10.12861/jrip.2013.41
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